Gallbladder cancer

Our analysis of worldwide research on gallbladder cancer

As part of the Continuous Update Project (CUP) – our ongoing programme to analyse global research on how diet, nutrition, physical activity and weight affect cancer risk and survival – we have analysed worldwide research to produce our report on gallbladder cancer.

Published in June 2015, the report is the most rigorous, systematic, global analysis of the scientific research currently available on diet, weight, physical activity and gallbladder cancer, and which of these factors increase or decrease the risk of developing the disease.

For the report, the global scientific research on diet, nutrition, physical activity and gallbladder cancer was gathered and analysed by a research team at Imperial College London, and then independently assessed by a panel of leading international scientists.

The total number of adults in the 14 studies from around the world reviewed for the report was around 13 million; and the total number of gallbladder cancer cases in the studies analysed for the report was around 8,300.

The report updates the gallbladder cancer section of our 2007 Second Expert Report

Key Findings

Strong evidence

  • There is strong evidence that being overweight or obese increases the risk of gallbladder cancer. Being overweight or obese is assessed by body mass index (BMI).

This finding remains unchanged from the 2007 Second Expert Report.

Gallbladder cancer matrix


To reduce the risk of developing gallbladder cancer:

1. Maintain a healthy weight.

This advice forms part of our existing Cancer Prevention Recommendations. Our Cancer Prevention Recommendations are for preventing cancer in general and include eating a healthy diet, being physically active and maintaining a healthy weight.

A more detailed overview of the findings is provided in the Executive Summary of the report.